Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Yap1  yes-associated protein 1   (Synonyms: Yap, Yki, yorkie)
Results	Reference
1	J:331266 Abou Nader N, Menard A, Levasseur A, St-Jean G, Boerboom D, Zamberlam G, Boyer A, Targeted Disruption of Lats1 and Lats2 in Mice Impairs Testis Development and Alters Somatic Cell Fate. Int J Mol Sci. 2022 Nov 5;23(21)
1	J:226938 Bagherie-Lachidan M, Reginensi A, Pan Q, Zaveri HP, Scott DA, Blencowe BJ, Helmbacher F, McNeill H, Stromal Fat4 acts non-autonomously with Dchs1/2 to restrict the nephron progenitor pool. Development. 2015 Aug 1;142(15):2564-73
1	J:234361 Deng Y, Wu A, Li P, Li G, Qin L, Song H, Mak KK, Yap1 Regulates Multiple Steps of Chondrocyte Differentiation during Skeletal Development and Bone Repair. Cell Rep. 2016 Mar 8;14(9):2224-37
1	J:290788 Gnedeva K, Wang X, McGovern MM, Barton M, Tao L, Trecek T, Monroe TO, Llamas J, Makmura W, Martin JF, Groves AK, Warchol M, Segil N, Organ of Corti size is governed by Yap/Tead-mediated progenitor self-renewal. Proc Natl Acad Sci U S A. 2020 Jun 16;117(24):13552-13561
1	J:333075 Goodwin AF, Chen CP, Vo NT, Bush JO, Klein OD, YAP/TAZ Regulate Elevation and Bone Formation of the Mouse Secondary Palate. J Dent Res. 2020 Nov;99(12):1387-1396
1	J:302131 Hu HB, Song ZQ, Song GP, Li S, Tu HQ, Wu M, Zhang YC, Yuan JF, Li TT, Li PY, Xu YL, Shen XL, Han QY, Li AL, Zhou T, Chun J, Zhang XM, Li HY, LPA signaling acts as a cell-extrinsic mechanism to initiate cilia disassembly and promote neurogenesis. Nat Commun. 2021 Jan 28;12(1):662
1*	J:283394 Hughes LJ, Park R, Lee MJ, Terry BK, Lee DJ, Kim H, Cho SH, Kim S, Yap/Taz are required for establishing the cerebellar radial glia scaffold and proper foliation. Dev Biol. 2020 Jan 1;457(1):150-162
1	J:288374 Kostic M, Paridaen JTML, Long KR, Kalebic N, Langen B, Grubling N, Wimberger P, Kawasaki H, Namba T, Huttner WB, YAP Activity Is Necessary and Sufficient for Basal Progenitor Abundance and Proliferation in the Developing Neocortex. Cell Rep. 2019 Apr 23;27(4):1103-1118.e6
1*	J:309394 Kwon HJ, Li L, Jung HS, Hippo pathway/Yap regulates primary enamel knot and dental cusp patterning in tooth morphogenesis. Cell Tissue Res. 2015 Nov;362(2):447-51
1	J:317151 Lavado A, Gangwar R, Pare J, Wan S, Fan Y, Cao X, YAP/TAZ maintain the proliferative capacity and structural organization of radial glial cells during brain development. Dev Biol. 2021 Dec;480:39-49
1*	J:199301 Lavado A, He Y, Pare J, Neale G, Olson EN, Giovannini M, Cao X, Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators. Development. 2013 Aug;140(16):3323-34
1	J:240835 Li CY, Hu J, Lu H, Lan J, Du W, Galicia N, Klein OD, alphaE-catenin inhibits YAP/TAZ activity to regulate signalling centre formation during tooth development. Nat Commun. 2016 Jul 13;7:12133
1*	J:170274 Li L, Kwon HJ, Harada H, Ohshima H, Cho SW, Jung HS, Expression patterns of ABCG2, Bmi-1, Oct-3/4, and Yap in the developing mouse incisor. Gene Expr Patterns. 2011 Mar-Apr;11(3-4):163-70
1	J:244106 Lin C, Yao E, Zhang K, Jiang X, Croll S, Thompson-Peer K, Chuang PT, YAP is essential for mechanical force production and epithelial cell proliferation during lung branching morphogenesis. Elife. 2017 Mar 21;6:e21130
1	J:224422 Liu M, Zhao S, Lin Q, Wang XP, YAP regulates the expression of Hoxa1 and Hoxc13 in mouse and human oral and skin epithelial tissues. Mol Cell Biol. 2015 Apr;35(8):1449-61
1	J:267913 Liu WA, Chen S, Li Z, Lee CH, Mirzaa G, Dobyns WB, Ross ME, Zhang J, Shi SH, PARD3 dysfunction in conjunction with dynamic HIPPO signaling drives cortical enlargement with massive heterotopia. Genes Dev. 2018 Jun 1;32(11-12):763-780
1	J:213950 Mahoney JE, Mori M, Szymaniak AD, Varelas X, Cardoso WV, The hippo pathway effector Yap controls patterning and differentiation of airway epithelial progenitors. Dev Cell. 2014 Jul 28;30(2):137-50
1	J:307229 McNeill H, Reginensi A, Lats1/2 Regulate Yap/Taz to Control Nephron Progenitor Epithelialization and Inhibit Myofibroblast Formation. J Am Soc Nephrol. 2017 Mar;28(3):852-861
1	J:320686 Molina LM, Zhu J, Li Q, Pradhan-Sundd T, Krutsenko Y, Sayed K, Jenkins N, Vats R, Bhushan B, Ko S, Hu S, Poddar M, Singh S, Tao J, Sundd P, Singhi A, Watkins S, Ma X, Benos PV, Feranchak A, Michalopoulos G, Nejak-Bowen K, Watson A, Bell A, Monga SP, Compensatory hepatic adaptation accompanies permanent absence of intrahepatic biliary network due to YAP1 loss in liver progenitors. Cell Rep. 2021 Jul 6;36(1):109310
1	J:253963 Moon KH, Kim HT, Lee D, Rao MB, Levine EM, Lim DS, Kim JW, Differential Expression of NF2 in Neuroepithelial Compartments Is Necessary for Mammalian Eye Development. Dev Cell. 2018 Jan 8;44(1):13-28.e3
1*	J:306471 Niki Y, Kobayashi Y, Moriyama K, Expression pattern of transcriptional enhanced associate domain family member 1 (Tead1) in developing mouse molar tooth. Gene Expr Patterns. 2021 Jun;40:119182
1	J:195266 Reginensi A, Scott RP, Gregorieff A, Bagherie-Lachidan M, Chung C, Lim DS, Pawson T, Wrana J, McNeill H, Yap- and Cdc42-Dependent Nephrogenesis and Morphogenesis during Mouse Kidney Development. PLoS Genet. 2013 Mar;9(3):e1003380
1	J:266255 Scavuzzo MA, Hill MC, Chmielowiec J, Yang D, Teaw J, Sheng K, Kong Y, Bettini M, Zong C, Martin JF, Borowiak M, Endocrine lineage biases arise in temporally distinct endocrine progenitors during pancreatic morphogenesis. Nat Commun. 2018 Aug 22;9(1):3356
1	J:243381 Serafimidis I, Rodriguez-Aznar E, Lesche M, Yoshioka K, Takuwa Y, Dahl A, Pan D, Gavalas A, Pancreas lineage allocation and specification are regulated by sphingosine-1-phosphate signalling. PLoS Biol. 2017 Mar;15(3):e2000949
1	J:286313 Shea CA, Rolfe RA, McNeill H, Murphy P, Localization of YAP activity in developing skeletal rudiments is responsive to mechanical stimulation. Dev Dyn. 2020 Apr;249(4):523-542
1	J:206876 Song JY, Park R, Kim JY, Hughes L, Lu L, Kim S, Johnson RL, Cho SH, Dual function of Yap in the regulation of lens progenitor cells and cellular polarity. Dev Biol. 2014 Feb 15;386(2):281-90
1	J:239794 Szymaniak AD, Mahoney JE, Cardoso WV, Varelas X, Crumbs3-Mediated Polarity Directs Airway Epithelial Cell Fate through the Hippo Pathway Effector Yap. Dev Cell. 2015 Aug 10;34(3):283-96
1	J:326480 Terry BK, Park R, Cho SH, Crino PB, Kim S, Abnormal activation of Yap/Taz contributes to the pathogenesis of tuberous sclerosis complex. Hum Mol Genet. 2022 Jun 22;31(12):1979-1996
1	J:290308 van Soldt BJ, Qian J, Li J, Tang N, Lu J, Cardoso WV, Yap and its subcellular localization have distinct compartment-specific roles in the developing lung. Development. 2019 May 1;146(9):dev175810
1	J:272593 Volckaert T, Yuan T, Yuan J, Boateng E, Hopkins S, Zhang JS, Thannickal VJ, Fassler R, De Langhe SP, Hippo signaling promotes lung epithelial lineage commitment by curbing Fgf10 and beta-catenin signaling. Development. 2019 Jan 16;146(2):dev166454
1	J:245881 Wang X, Freire Valls A, Schermann G, Shen Y, Moya IM, Castro L, Urban S, Solecki GM, Winkler F, Riedemann L, Jain RK, Mazzone M, Schmidt T, Fischer T, Halder G, Ruiz de Almodovar C, YAP/TAZ Orchestrate VEGF Signaling during Developmental Angiogenesis. Dev Cell. 2017 Sep 11;42(5):462-478.e7
1	J:326028 Yang Y, Jiang X, Li X, Sun K, Zhu X, Zhou B, Specific ablation of Hippo signalling component Yap1 in retinal progenitors and Muller cells results in late onset retinal degeneration. J Cell Physiol. 2022 Jun;237(6):2673-2689
1	J:317198 Yang Y, Paivinen P, Xie C, Krup AL, Makela TP, Mostov KE, Reiter JF, Ciliary Hedgehog signaling patterns the digestive system to generate mechanical forces driving elongation. Nat Commun. 2021 Dec 10;12(1):7186
1	J:290855 Yu W, Sun Z, Sweat Y, Sweat M, Venugopalan SR, Eliason S, Cao H, Paine ML, Amendt BA, Pitx2-Sox2-Lef1 interactions specify progenitor oral/dental epithelial cell signaling centers. Development. 2020 Jun 4;147(11):dev186023